SCHEMBL1809377

SCHEMBL1809377

O=C(Oc1ccc2ccccc2c1)Oc1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
MAPT P10636 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HSD17B10 Q99714 1/20 0.58
PTPN7 P35236 1/20 0.55
MMP1 P03956 2/20 0.53
MMP12 P39900 1/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 1/20 0.52
FABP7 O15540 1/20 0.51
FABP3 P05413 1/20 0.51
BCHE P06276 1/20 0.51
FAAH O00519 1/20 0.51
EPHX1 P07099 1/20 0.51
MMP2 P08253 1/20 0.51
CES2 O00748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808182 0.94 KMT2A (0.65) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL11444479 0.91 KMT2A (0.61) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL17641642 0.89 KMT2A (0.54) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL14514195 0.88 KMT2A (0.58) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL21881869 0.86 KMT2A (0.66) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL9574400 0.85 KMT2A (0.54) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL6443500 0.84 KMT2A (0.63) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL1563903 0.84 KMT2A (0.69) KMT2AMEN1MAPTTDP1ALDH1A1
Naphthalene SCHEMBL1131780 0.84 KMT2A (0.69) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL29937281 0.84 KMT2A (0.69) KMT2AMEN1MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999021561-A1 METHOD FOR TREATMENT OF DISORDERS OF ATTENTION DAVIS BONNIE M (US) 1999-05-06 WO claimed
US-4414230-A BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-08 US claimed
CN-108290820-B Method for recovering aromatic alcohol from melt polymerization and system for recovering same 沙特基础工业全球技术有限公司 2021-10-01 CN disclosed
EP-3038747-B1 TRANSESTERIFICATION OF AROMATIC ALCOHOLS USING A HETEROGENEOUS CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-08 EP disclosed
EP-3383835-B1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-24 EP disclosed
WO-2019048986-A1 METHOD FOR PRODUCING A POLYCARBONATE ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-14 WO disclosed
EP-2711353-B1 Process for the continuous manufacture of aryl alkyl carbonate and diaryl carbonate using vapor recompression SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-10-31 EP disclosed
EP-3383835-A1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC Global Technologies B.V. (NL) 2018-10-10 EP disclosed
US-10059652-B2 Heterogeneous catalysts for the transesterification of aromatic alcohols; and methods of making and use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-08-28 US disclosed
EP-2970096-B1 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-08-08 EP disclosed
EP-2816068-B1 Process for the manufacture of polycarbonate compositions SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-12-27 EP disclosed
US-5344954-A Ester interchange, countercurrent flow in two-stage column reactor BAYER AKTIENGESELLSCHAFT (DE) 1994-09-06 US disclosed
EP-0608710-A1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1994-08-03 EP disclosed
US-5334742-A Thermodynamic transesterification in presence of catalysts BAYER AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed
EP-0582930-A2 Process for the preparation of diarylcarbonates BAYER AG (DE) 1994-02-16 EP disclosed
EP-0582931-A2 Process for the continuous preparation of diarylcarbonates from dialkylcarbonates BAYER AG (DE) 1994-02-16 EP disclosed
EP-0572870-A1 Process for the production of organic carbonates with at least one aromatic ester group BAYER AG (DE) 1993-12-08 EP disclosed
US-4751144-A Denture base made of thermoplastic resin SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1988-06-14 US disclosed
US-4414230-A BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-08 US disclosed
US-4331558-A OLEFINS, MAGNESIUM OR MANGANESE HALIDE, ARYL CARBONATE, TITANIUM TETRAHALIDE, ORGANOALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1982-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10059652-B2 Heterogeneous catalysts for the transesterification of aromatic alcohols; and methods of making and use thereof ADH1C, ADH5, ADH1A KMT2A 2078/4885MEN1 2712/4885MAPT 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.