Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12111149 | 0.84 | TNKS2 (0.54) | PARP1KDM4ECYP3A4TNKS2ATM | |
| SCHEMBL15722032 | 0.79 | PARP1 (0.59) | PARP1POLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL29769683 | 0.79 | PARP1 (0.59) | PARP1POLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6515060 | 0.78 | TDP1 (0.42) | PARP1KDM4ECYP3A4TSHRHSD17B10 | |
| SCHEMBL7622606 | 0.78 | KIF11 (0.41) | KDM4ECYP3A4TSHRHSD17B10KMT2A | |
| SCHEMBL1424370 | 0.75 | PARP1 (0.55) | PARP1POLB | |
| SCHEMBL6755253 | 0.75 | PARP1 (0.54) | PARP1POLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6756139 | 0.75 | PARP1 (0.47) | PARP1POLBKDM4EKMT2AMEN1 | |
| SCHEMBL29900512 | 0.74 | PARP1 (1.00) | PARP1KMT2AMEN1TNKS2 | |
| SCHEMBL168776 | 0.74 | PARP1 (1.00) | PARP1KMT2AMEN1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051358-A | Condensed imdazole derivatives and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-05-15 | — | — | CN | disclosed |
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |