Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.57 |
| ▸ | RARA | P10276 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941999 | 0.85 | RARB (0.57) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL9477837 | 0.85 | RARB (0.57) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11562805 | 0.83 | MAPT (0.47) | RARBMAPTKMT2AMGLLTHRA | |
| SCHEMBL11546135 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11551030 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11547490 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11547828 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11551848 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11548632 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A | |
| SCHEMBL11551935 | 0.83 | RARB (0.64) | RARBRARAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064566-A | Chirally tilted, pyrimidines, pyridines, or pyrazines, stability | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-12 | — | — | US | disclosed |