Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206547 | 0.95 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1644791 | 0.89 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18828925 | 0.85 | THRB (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.84 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18854241 | 0.84 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16706192 | 0.84 | THRB (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL21300084 | 0.84 | THRB (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28715289 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18828910 | 0.82 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18854244 | 0.82 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| EP-3626705-B1 | ISOCYANATE PRODUCTION METHOD | ASAHI CHEMICAL IND (JP) | 2021-03-24 | — | — | EP | disclosed |
| US-20170145216-A1 | RHODAMINE-BASED COLORING COMPOSITION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170137553-A1 | GRAFT POLYMER, RESIN COLORED MATTER, METHOD FOR PRODUCING SAME, AND RESIN COMPOSITION CONTAINING RESIN COLORED MATTER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-05-18 | — | — | US | disclosed |