Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 7/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PYGM | P11217 | 3/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142250 | 1.00 | TK2 (0.64) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL9854795 | 0.90 | TK2 (0.78) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL2587710 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL1628082 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL5175300 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL6528897 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL1628084 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL2587708 | 0.88 | TK2 (0.83) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL8887226 | 0.88 | TK2 (0.61) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL2585320 | 0.86 | TK2 (0.69) | TK2CYP1A2CYP3A4TSHRTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433898-A2 | Analogs of oxetanyl purines and pyrimidines | ABBOTT LABORATORIES (US) | 1991-06-26 | — | — | EP | claimed |