Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855116 | 0.99 | HSD17B10 (0.47) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL9854976 | 0.95 | ACACB (0.41) | HSD17B10TSHRHSD11B1ACACBALDH1A1 | |
| SCHEMBL9855313 | 0.92 | HSD17B10 (0.50) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL9855817 | 0.91 | HSD17B10 (0.53) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL9854876 | 0.89 | FFAR1 (0.42) | ACACBFFAR1 | |
| SCHEMBL9855956 | 0.88 | ACACB (0.45) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL10510144 | 0.86 | HSD17B10 (0.37) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL10513511 | 0.86 | HSD17B10 (0.37) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL10512126 | 0.86 | HSD17B10 (0.37) | HSD17B10TSHRHSD11B1ACACBESR1 | |
| SCHEMBL9855249 | 0.85 | HSD17B10 (0.44) | HSD17B10TSHRHSD11B1ACACBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |