Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854914 | 0.95 | HSD17B10 (0.44) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL9855116 | 0.94 | HSD17B10 (0.47) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL9855956 | 0.92 | ACACB (0.45) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL9854876 | 0.91 | FFAR1 (0.42) | ACACBFFAR1GRM5 | |
| SCHEMBL9855313 | 0.87 | HSD17B10 (0.50) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL9855817 | 0.86 | HSD17B10 (0.53) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL9855061 | 0.85 | ACACB (0.41) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL10513511 | 0.85 | HSD17B10 (0.37) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL10510144 | 0.85 | HSD17B10 (0.37) | ACACBFFAR1HSD11B1HSD17B10TSHR | |
| SCHEMBL10512126 | 0.85 | HSD17B10 (0.37) | ACACBFFAR1HSD11B1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |