Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855328 | 1.00 | MCHR1 (0.40) | MCHR1APPCCNB2CDK1CCNB1 | |
| SCHEMBL9855487 | 1.00 | MCHR1 (0.40) | MCHR1APPCCNB2CDK1CCNB1 | |
| SCHEMBL9855225 | 0.99 | MCHR1 (0.41) | MCHR1APPCCNB2CDK1CCNB1 | |
| SCHEMBL9855700 | 0.95 | HRH2 (0.42) | MCHR1APPCCNB2CDK1CCNB1 | |
| SCHEMBL9854873 | 0.91 | ACACB (0.43) | MCHR1ACACBKCNH2 | |
| SCHEMBL10511071 | 0.91 | ACACB (0.43) | MCHR1ACACBKCNH2 | |
| SCHEMBL9855160 | 0.91 | ACACB (0.43) | MCHR1ACACBKCNH2 | |
| SCHEMBL9855235 | 0.91 | ACACB (0.43) | MCHR1ACACBKCNH2 | |
| SCHEMBL9855927 | 0.90 | ACACB (0.42) | MAPTACACBCYP19A1KCNH2 | |
| SCHEMBL9855319 | 0.90 | ACACB (0.42) | MAPTACACBCYP19A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |