Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855225 | 0.96 | MCHR1 (0.41) | HRH2HRH3MCHR1APPACACB | |
| SCHEMBL9855086 | 0.95 | MCHR1 (0.40) | HRH2HRH3MCHR1APPACACB | |
| SCHEMBL9855487 | 0.95 | MCHR1 (0.40) | HRH2HRH3MCHR1APPACACB | |
| SCHEMBL9855328 | 0.95 | MCHR1 (0.40) | HRH2HRH3MCHR1APPACACB | |
| SCHEMBL9855292 | 0.92 | APP (0.44) | MCHR1APPACACBKCNH2CCNB2 | |
| SCHEMBL9855008 | 0.90 | ACACB (0.45) | MCHR1ACACBMAPT | |
| SCHEMBL9855580 | 0.89 | ACACB (0.44) | ACACBMAPT | |
| SCHEMBL9855408 | 0.88 | ACACB (0.43) | MCHR1ACACB | |
| SCHEMBL9855280 | 0.86 | ACACB (0.44) | MCHR1ACACB | |
| SCHEMBL10512668 | 0.86 | HRH2 (0.35) | HRH2HRH3MCHR1APPACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |