Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855441 | 0.96 | HSD17B10 (0.43) | ACACBMCHR1FFAR1HSD17B10TSHR | |
| SCHEMBL9855410 | 0.94 | HSD17B10 (0.46) | ACACBMCHR1FFAR1HSD17B10TSHR | |
| SCHEMBL9855079 | 0.91 | FFAR1 (0.40) | ACACBMCHR1FFAR1ALDH1A1GRM5 | |
| SCHEMBL9855956 | 0.91 | ACACB (0.45) | ACACBMCHR1FFAR1HSD17B10TSHR | |
| SCHEMBL9855313 | 0.86 | HSD17B10 (0.50) | ACACBFFAR1HSD17B10TSHRHSD11B1 | |
| SCHEMBL10517953 | 0.86 | NPC1 (0.38) | ACACBFFAR1HSD17B10TSHRHSD11B1 | |
| SCHEMBL9855817 | 0.84 | HSD17B10 (0.53) | ACACBFFAR1HSD17B10TSHRHSD11B1 | |
| SCHEMBL9855636 | 0.84 | CYP2A6 (0.40) | ACACBMCHR1FFAR1GRM5 | |
| SCHEMBL9854976 | 0.84 | ACACB (0.41) | ACACBMCHR1FFAR1HSD17B10TSHR | |
| SCHEMBL9855061 | 0.84 | ACACB (0.41) | ACACBMCHR1FFAR1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |