Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323801 | 0.90 | POLB (1.00) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| Methyl Alcohol SCHEMBL27939411 | 0.88 | POLB (0.96) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL10747304 | 0.81 | POLB (0.71) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL340762 | 0.80 | L3MBTL1 (0.80) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL29682135 | 0.80 | L3MBTL1 (0.80) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| Ammonia Solution, Strong SCHEMBL28240461 | 0.78 | L3MBTL1 (0.77) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL10509566 | 0.77 | SMN1; SMN2 (0.75) | POLBSMN1; SMN2L3MBTL1GLAALDH1A1 | |
| SCHEMBL11637037 | 0.76 | POLB (0.54) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL5181008 | 0.75 | L3MBTL1 (1.00) | POLBSMN1; SMN2L3MBTL1GLAKDM4E | |
| SCHEMBL7406459 | 0.75 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2L3MBTL1GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263492-B1 | RETINOIDS, THEIR PREPARATION AND USE AS PHARMACEUTICAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | claimed |
| US-4900478-A | SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | disclosed |