Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855993 | 0.97 | DRD2 (0.42) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855799 | 0.96 | DRD2 (0.41) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855547 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855015 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855232 | 0.94 | DRD2 (0.43) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9854825 | 0.93 | DRD2 (0.42) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855323 | 0.93 | DRD2 (0.42) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855327 | 0.93 | DRD2 (0.42) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855412 | 0.93 | DRD2 (0.42) | DRD2DRD4DRD3ACACBMAOA | |
| SCHEMBL9855919 | 0.91 | DRD2 (0.41) | DRD2DRD4DRD3ACACBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |