Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855545 | 0.96 | HSD17B10 (0.43) | ACACBHSD17B10TSHRHSD11B1PTPN11 | |
| SCHEMBL9855061 | 0.95 | ACACB (0.41) | ACACBHSD17B10TSHRHSD11B1CA1 | |
| SCHEMBL9855124 | 0.94 | HSD17B10 (0.46) | ACACBHSD17B10TSHRHSD11B1PTPN11 | |
| SCHEMBL9856085 | 0.94 | ACACB (0.41) | ACACBHSD17B10TSHRHSD11B1FFAR1 | |
| SCHEMBL9855818 | 0.93 | HSD17B10 (0.43) | ACACBHSD17B10TSHRHSD11B1FFAR1 | |
| SCHEMBL9855923 | 0.93 | HSD17B10 (0.43) | ACACBHSD17B10TSHRHSD11B1FFAR1 | |
| SCHEMBL9855380 | 0.92 | ACACB (0.40) | ACACBFFAR1CYP19A1GRM5 | |
| SCHEMBL9855595 | 0.92 | HSD17B10 (0.46) | ACACBHSD17B10TSHRHSD11B1PTPN11 | |
| SCHEMBL9855080 | 0.92 | HSD17B10 (0.46) | ACACBHSD17B10TSHRHSD11B1PTPN11 | |
| SCHEMBL9855314 | 0.92 | HSD17B10 (0.46) | ACACBHSD17B10TSHRHSD11B1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |