Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855291 | 0.96 | ACACB (0.40) | ACACBFFAR1FFAR4CYP19A1GRM5 | |
| SCHEMBL9855061 | 0.95 | ACACB (0.41) | ACACBFFAR1FFAR4CYP19A1GRM5 | |
| SCHEMBL9855244 | 0.94 | HSD17B10 (0.42) | ACACBFFAR1FFAR4CYP19A1TSHR | |
| SCHEMBL9855622 | 0.94 | HSD17B10 (0.42) | ACACBFFAR1FFAR4CYP19A1TSHR | |
| SCHEMBL9854921 | 0.94 | HSD17B10 (0.42) | ACACBFFAR1FFAR4CYP19A1TSHR | |
| SCHEMBL9855353 | 0.94 | ACACB (0.41) | ACACBFFAR1FFAR4CYP19A1GRM5 | |
| SCHEMBL9855818 | 0.93 | HSD17B10 (0.43) | ACACBFFAR1FFAR4CYP19A1TSHR | |
| SCHEMBL9855923 | 0.93 | HSD17B10 (0.43) | ACACBFFAR1FFAR4CYP19A1TSHR | |
| SCHEMBL9855380 | 0.92 | ACACB (0.40) | ACACBFFAR1CYP19A1GRM5 | |
| SCHEMBL9855080 | 0.92 | HSD17B10 (0.46) | ACACBFFAR1FFAR4CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |