Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855247 | 0.96 | ACACB (0.42) | ACACBDRD2DRD4DRD3NQO1 | |
| SCHEMBL9855717 | 0.89 | DRD2 (0.44) | ACACBDRD2DRD4DRD3NQO1 | |
| SCHEMBL9855233 | 0.89 | DRD2 (0.44) | ACACBDRD2DRD4DRD3MAOA | |
| SCHEMBL9855059 | 0.89 | DRD2 (0.44) | ACACBDRD2DRD4DRD3NPC1 | |
| SCHEMBL9855121 | 0.87 | DRD2 (0.43) | ACACBDRD2DRD4DRD3NQO1 | |
| SCHEMBL9854919 | 0.87 | DRD2 (0.43) | ACACBDRD2DRD4DRD3MAOA | |
| SCHEMBL10512110 | 0.87 | DRD2 (0.37) | ACACBDRD2DRD4DRD3NPC1 | |
| SCHEMBL9855226 | 0.86 | DRD2 (0.42) | ACACBDRD2DRD4DRD3MAOA | |
| SCHEMBL9855208 | 0.86 | DRD2 (0.42) | ACACBDRD2DRD4DRD3MAOA | |
| SCHEMBL9854890 | 0.86 | DRD2 (0.42) | ACACBDRD2DRD4DRD3NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |