SCHEMBL9855601

SCHEMBL9855601

O=C(O)CN(CCN(CC(=O)O)CP(=O)(O)O)CP(=O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.59
EYA2 O00167 1/20 0.59
APP P05067 1/20 0.59
ACE P12821 1/20 0.59
BLM P54132 3/20 0.56
PMP22 Q01453 2/20 0.56
LMNA P02545 2/20 0.56
TSHR P16473 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ALOX15 P16050 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
CYP2C19 P33261 1/20 0.56
ADRA1A P35348 1/20 0.56
DRD3 P35462 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HRH3 Q9Y5N1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395267 0.98 TDP1 (0.56) TDP1EYA2APPACEBLM
SCHEMBL6428959 0.96 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL2241682 0.93 TDP1 (0.64) TDP1EYA2APPACEBLM
SCHEMBL1395023 0.93 TDP1 (0.64) TDP1EYA2APPACEBLM
SCHEMBL6427963 0.91 TDP1 (0.61) TDP1EYA2APPACEBLM
SCHEMBL6428138 0.91 TDP1 (0.61) TDP1EYA2APPACEBLM
SCHEMBL67368 0.90 TDP1 (0.50) TDP1EYA2APPACEBLM
SCHEMBL27709276 0.90 TDP1 (0.50) TDP1EYA2APPACEBLM
SCHEMBL65674 0.90 TDP1 (0.50) TDP1EYA2APPACEBLM
SCHEMBL11895837 0.90 TDP1 (0.50) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170239182-A1 PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS HAYES MARK E (US) 2017-08-24 US claimed
US-20170231910-A1 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM HAYES MARK E (US) 2017-08-17 US claimed
US-20140271825-A1 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM ZONEONE PHARMA, INC. 2014-09-18 US claimed
US-11766441-B2 Oral liquid compositions including chlorpromazine Genus Lifesciences Inc. (US) 2023-09-26 US disclosed
EP-4221714-A1 ORAL LIQUID COMPOSITIONS INCLUDING CHLORPROMAZINE Genus Lifesciences Inc. (US) 2023-08-09 EP disclosed
US-20170239182-A1 PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS HAYES MARK E (US) 2017-08-24 US disclosed
US-20170231910-A1 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM HAYES MARK E (US) 2017-08-17 US disclosed
US-20170128366-A1 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM ZONEONE PHARMA INC (US) 2017-05-11 US disclosed
WO-2016025559-A1 PHARMACEUTICAL FORMULATIONS OF AND METHODS TO PREPARE CHELATING AGENTS FOR EFFICIENT METAL REMOVAL TREATMENT SYSTEMS ZONEONE PHARMA, INC. (US) 2016-02-18 WO disclosed
WO-2016025611-A2 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM ZONEONE PHARMA, INC. (US) 2016-02-18 WO disclosed
US-20140271825-A1 PHARMACEUTICAL FORMULATIONS OF CHELATING AGENTS AS A METAL REMOVAL TREATMENT SYSTEM ZONEONE PHARMA, INC. 2014-09-18 US disclosed
US-5068404-A Heating aqueous solution of di- or tri-alkali metal salt of N-alkyl-N-phosphonomethylglycine MONSANTO COMPANY (US) 1991-11-26 US disclosed
EP-0187633-B1 THERMAL DEALKYLATION OF N-ALKYL N-PHOSPHONOMETHYLGLYCINE Monsanto Company (US) 1989-03-01 EP disclosed
EP-0187633-A1 Thermal dealkylation of n-alkyl n-phosphonomethylglycine Monsanto Company (US) 1986-07-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766441-B2 Oral liquid compositions including chlorpromazine WIZ, CPNE4, CYP3A5 TDP1 1178/4885EYA2 2984/4885APP 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.