Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855538 | 0.88 | HMGCR (0.35) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855534 | 0.88 | HMGCR (0.35) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855396 | 0.87 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855395 | 0.87 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9622023 | 0.87 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855706 | 0.81 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855712 | 0.81 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855198 | 0.80 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855126 | 0.77 | HMGCR (0.34) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855132 | 0.77 | HMGCR (0.34) | HMGCRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |