Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855395 | 1.00 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9622023 | 1.00 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9855538 | 0.92 | HMGCR (0.35) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9855534 | 0.92 | HMGCR (0.35) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9855675 | 0.87 | ALDH1A1 (0.35) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855198 | 0.86 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9622390 | 0.86 | HMGCR (0.38) | HMGCRADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9855703 | 0.85 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9855706 | 0.85 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3HDAC3 | |
| SCHEMBL9622380 | 0.85 | HMGCR (0.43) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |