Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855877 | 1.00 | SSTR3 (0.35) | SSTR3ALDH1A1KLK7CACNA1BHMGCR | |
| SCHEMBL9855132 | 0.95 | HMGCR (0.34) | SSTR3HMGCRDGAT2 | |
| SCHEMBL9855126 | 0.95 | HMGCR (0.34) | SSTR3HMGCRDGAT2 | |
| SCHEMBL9855231 | 0.87 | HMGCR (0.40) | ALDH1A1HMGCR | |
| SCHEMBL9855180 | 0.82 | HMGCR (0.42) | HMGCR | |
| SCHEMBL9855198 | 0.81 | HMGCR (0.36) | HMGCR | |
| SCHEMBL9855396 | 0.80 | HMGCR (0.36) | HMGCR | |
| SCHEMBL9855706 | 0.80 | HMGCR (0.36) | HMGCR | |
| SCHEMBL9855712 | 0.80 | HMGCR (0.36) | HMGCR | |
| SCHEMBL9622023 | 0.80 | HMGCR (0.36) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |