Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL985170 | 0.99 | SMYD3 (0.40) | SMYD3BRD4BTKALDH1A1KMT2A | |
| SCHEMBL984182 | 0.94 | SMYD3 (0.41) | SMYD3BTKALDH1A1KMT2ASCN8A | |
| SCHEMBL981859 | 0.94 | SMYD3 (0.41) | SMYD3BTKALDH1A1KMT2ASCN8A | |
| SCHEMBL984446 | 0.92 | BTK (0.40) | BRD4BTKALDH1A1KMT2ASCN8A | |
| SCHEMBL981978 | 0.91 | NPY5R (0.38) | BRD4BTKALDH1A1KMT2ASCN8A | |
| SCHEMBL983050 | 0.91 | BRD4 (0.37) | SMYD3BRD4ALDH1A1KMT2ASCN8A | |
| SCHEMBL984898 | 0.90 | GRIN1 (0.40) | BRD4BTKALDH1A1KMT2ASCN8A | |
| Hydrochloric Acid SCHEMBL985798 | 0.90 | ACKR3 (0.38) | BRD4ALDH1A1KMT2ASCN8ASCN10A | |
| SCHEMBL984905 | 0.90 | KDM1A (0.42) | SMYD3BTKKDM1AHPGDPBK | |
| SCHEMBL984599 | 0.90 | BTK (0.39) | SMYD3BTKKDM1APBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | PDE5A, PDE3A, PDE2A | SMYD3 1287/4885BRD4 1299/4885BTK 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.