Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.37 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982008 | 0.91 | BTK (0.40) | BTKMRGPRX1 | |
| SCHEMBL981859 | 0.91 | SMYD3 (0.41) | BTKSMYD3PBKKDM1A | |
| SCHEMBL984182 | 0.91 | SMYD3 (0.41) | BTKSMYD3PBKKDM1A | |
| SCHEMBL983264 | 0.90 | BTK (0.40) | BTKMRGPRX1 | |
| SCHEMBL983586 | 0.90 | BTK (0.35) | BTKMRGPRX1 | |
| SCHEMBL983559 | 0.90 | PTK2 (0.39) | PBKKDM1AMRGPRX1 | |
| SCHEMBL985596 | 0.90 | SMYD3 (0.41) | BTKSMYD3PBKKDM1A | |
| Hydrochloric Acid SCHEMBL985170 | 0.89 | SMYD3 (0.40) | BTKSMYD3PBKKDM1A | |
| SCHEMBL983256 | 0.88 | BTK (0.42) | BTKMRGPRX1 | |
| SCHEMBL983145 | 0.88 | BTK (0.44) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | PDE5A, PDE3A, PDE2A | BTK 1977/4885SMYD3 1287/4885PBK 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.