Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430238 | 0.85 | ADA (0.53) | ADAENPP1P2RY1ADORA3ADORA1 | |
| SCHEMBL766552 | 0.83 | ENPP1 (0.60) | ENPP1P2RY1POLB | |
| SCHEMBL16174396 | 0.83 | ENPP1 (0.60) | ENPP1P2RY1POLB | |
| SCHEMBL2788058 | 0.83 | ENPP1 (0.60) | ENPP1P2RY1POLB | |
| SCHEMBL15832423 | 0.81 | ADA (0.57) | ADAENPP1P2RY1ADORA3ADORA1 | |
| SCHEMBL16360128 | 0.81 | ADA (0.57) | ADAENPP1P2RY1ADORA3ADORA1 | |
| SCHEMBL10432419 | 0.81 | ADA (0.57) | ADAENPP1P2RY1ADORA3ADORA1 | |
| SCHEMBL9194199 | 0.81 | ADORA1 (0.63) | ADORA3ADORA1ADORA2APOLBDPP4 | |
| SCHEMBL9194212 | 0.81 | ADORA1 (0.63) | ADORA3ADORA1ADORA2APOLBDPP4 | |
| SCHEMBL10446527 | 0.80 | ADA (0.58) | ADAENPP1P2RY1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |