Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334578 | 0.87 | CYP2D6 (0.49) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL1786485 | 0.85 | TSHR (0.53) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL14690196 | 0.85 | TSHR (0.53) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL1071781 | 0.84 | CYP2D6 (0.50) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL1070313 | 0.84 | CYP1A2 (0.49) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL12863873 | 0.83 | TSHR (0.52) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL1788436 | 0.82 | TSHR (0.50) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL5941299 | 0.81 | TSHR (0.53) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL18489634 | 0.81 | TSHR (0.49) | MEN1KMT2ATSHRTP53CYP2D6 | |
| SCHEMBL20256023 | 0.80 | PRKCA (0.54) | MEN1KMT2ATSHRTP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416822-A2 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | claimed |