SCHEMBL9856671

SCHEMBL9856671

CCC(CC(=O)OC)NC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 2/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP8 P22894 1/20 0.39
CA9 Q16790 1/20 0.39
MGAM O43451 2/20 0.37
GAA P10253 2/20 0.37
SI P14410 2/20 0.37
MGAM2 Q2M2H8 2/20 0.37
HSD17B10 Q99714 1/20 0.37
PKM P14618 1/20 0.33
ANPEP P15144 1/20 0.32
ENPEP Q07075 1/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
TET2 Q6N021 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12295404 1.00 TSHR (0.40) TSHRCA1CA2CA12MMP1
SCHEMBL18479683 0.84 TSHR (0.39) TSHRCA1CA2CA12MMP1
SCHEMBL12295406 0.82 TSHR (0.40) TSHRCA12MGAMGAASI
SCHEMBL12940852 0.82 TSHR (0.40) TSHRCA12MGAMGAASI
SCHEMBL10000224 0.80 MGAM (0.46) TSHRCA12CA9MGAMGAA
SCHEMBL16982706 0.80 TSHR (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL13936455 0.80 MGAM (0.41) TSHRMGAMGAASIMGAM2
SCHEMBL23222856 0.78 TSHR (0.37) TSHRMGAMGAASIMGAM2
SCHEMBL14733495 0.78 TSHR (0.48) TSHRCA1CA2CA12MMP1
SCHEMBL1405643 0.78 CA12 (0.41) TSHRCA1CA2CA12MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0269043-B1 PROCESS FOR PREPARING 3 PENTENOIC ACID ESTERS FROM 2-PENTENOIC ACID ESTERS BASF Aktiengesellschaft (DE) 1991-08-21 EP disclosed
US-4845269-A Preparation of 3-pentenoates from 2-pentenoates BASF AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0269043-A2 Process for preparing 3 pentenoic acid esters from 2-pentenoic acid esters BASF Aktiengesellschaft (DE) 1988-06-01 EP disclosed