Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CRAT | P43155 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311284 | 0.89 | MGAM (0.44) | MGAMGAASIMGAM2CRAT | |
| SCHEMBL21327975 | 0.84 | MGAM (0.46) | MGAMGAASIMGAM2CRAT | |
| SCHEMBL11315545 | 0.80 | CRAT (0.37) | MGAMGAASIMGAM2CRAT | |
| SCHEMBL7734523 | 0.80 | ALDH1A1 (0.46) | CA12MMP1CA9MGAMGAA | |
| SCHEMBL422585 | 0.79 | — | — | |
| SCHEMBL9856671 | 0.78 | TSHR (0.40) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL7731906 | 0.78 | CRAT (0.41) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL12295404 | 0.78 | TSHR (0.40) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL1144276 | 0.78 | CRAT (0.41) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL1144295 | 0.78 | CRAT (0.41) | CA12CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975170-B9 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-11-02 | — | — | EP | disclosed |
| EP-1975170-B1 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-7569730-B2 | Bisphosphine ligand | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1975170-A1 | Bisphosphine ligands for asymmetric syntheses | Daiichi Fine Chemical Co., Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | GPR4, HRH4, GPR3 | CA12 2653/4885CA1 1661/4885CA2 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.