Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.49 |
| ▸ | PLK1 | P53350 | 3/20 | 0.48 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268362 | 0.84 | NR1H4 (0.54) | NR1H4PLK1PLK3 | |
| SCHEMBL9713608 | 0.82 | FFAR1 (0.61) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9857044 | 0.81 | NR1H4 (0.59) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL2269617 | 0.80 | KDM4E (0.54) | NR1H4 | |
| SCHEMBL9856852 | 0.80 | NR1H4 (0.58) | FFAR1NR1H4CYSLTR2CYSLTR1PLK1 | |
| SCHEMBL9857021 | 0.79 | FFAR1 (0.63) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9713940 | 0.79 | NR1H4 (0.52) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9857614 | 0.78 | NR1H4 (0.55) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL1746597 | 0.77 | FFAR1 (1.00) | FFAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL9856976 | 0.77 | NR1H4 (0.54) | FFAR1NR1H4CYSLTR2CYSLTR1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |