Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283405 | 0.95 | HMGCR (0.60) | HMGCR | |
| SCHEMBL14283436 | 0.95 | HMGCR (0.60) | HMGCR | |
| SCHEMBL14283432 | 0.86 | HMGCR (0.50) | HMGCR | |
| SCHEMBL9857125 | 0.84 | HMGCR (0.64) | HMGCR | |
| SCHEMBL9856784 | 0.83 | HMGCR (0.63) | HMGCR | |
| SCHEMBL9856756 | 0.82 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9856821 | 0.82 | HMGCR (0.75) | HMGCR | |
| SCHEMBL9856817 | 0.82 | HMGCR (0.75) | HMGCR | |
| SCHEMBL9856946 | 0.82 | HMGCR (0.61) | HMGCR | |
| SCHEMBL9856838 | 0.81 | HMGCR (0.60) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436851-A1 | Compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1991-07-17 | — | — | EP | disclosed |