SCHEMBL9856898

SCHEMBL9856898

Cc1ccc(-c2ccc3ccccc3c2C=O)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.47
CYP1A2 P05177 4/20 0.44
CYP2A6 P11509 4/20 0.44
MAPT P10636 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
THRB P10828 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15701852 0.85 GRM2 (0.49) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL9857438 0.84 CYP1A2 (0.49) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL808500 0.83 ERN1 (0.64) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL29391032 0.83 ERN1 (0.64) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL26661895 0.82 ERN1 (0.45) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL9856910 0.79 CYP1A2 (0.42) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL22871880 0.77 ERN1 (0.49) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL6548332 0.76 CA12 (0.54) CYP1A2CYP2A6MAPTTDP1GAA
SCHEMBL230035 0.76 ERN1 (0.60) ERN1CYP1A2CYP2A6MAPTCYP2C9
SCHEMBL29357470 0.76 ERN1 (0.60) ERN1CYP1A2CYP2A6MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426846-A1 FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed