Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507659 | 1.00 | TSHR (0.44) | TSHRSLC6A4SLC6A3POLBATM | |
| SCHEMBL10507651 | 1.00 | TSHR (0.44) | TSHRSLC6A4SLC6A3POLBATM | |
| SCHEMBL10509350 | 0.81 | TSHR (0.43) | TSHRATMHTTALDH1A1EPHX1 | |
| SCHEMBL9857506 | 0.81 | TSHR (0.43) | TSHRATMHTTALDH1A1EPHX1 | |
| SCHEMBL10509356 | 0.81 | TSHR (0.43) | TSHRATMHTTALDH1A1EPHX1 | |
| SCHEMBL10506848 | 0.81 | TSHR (0.42) | TSHRPOLBATMALDH1A1 | |
| SCHEMBL10506858 | 0.81 | TSHR (0.42) | TSHRPOLBATMALDH1A1 | |
| SCHEMBL9857686 | 0.81 | TSHR (0.42) | TSHRPOLBATMALDH1A1 | |
| SCHEMBL6837232 | 0.81 | TSHR (0.49) | TSHRPOLBHTTEPHX1ACHE | |
| SCHEMBL8406156 | 0.81 | TSHR (0.49) | TSHRPOLBHTTEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301401-B1 | LEUKOTRIENE ANTAGONISTS, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE TREATMENT OF ILLNESSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4851440-A | ASTHMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0301401-A2 | Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-01 | — | — | EP | disclosed |