Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | FHIT | P49789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857545 | 0.86 | SLC22A6 (0.44) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| SCHEMBL9685561 | 0.85 | CYP3A4 (0.47) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| SCHEMBL9180474 | 0.85 | CYP3A4 (0.57) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| SCHEMBL9185744 | 0.84 | SLC22A6 (0.62) | FGFR1SLC22A6CYP3A4ENPP1FBP1 | |
| SCHEMBL6334793 | 0.84 | FGFR1 (0.61) | FGFR1SLC22A6CYP3A4ENPP1FBP1 | |
| Ammonia Solution, Strong SCHEMBL9128742 | 0.84 | CYP3A4 (0.56) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| Ammonia Solution, Strong SCHEMBL9128718 | 0.84 | CYP3A4 (0.56) | FGFR1SLC22A6CYP3A4ENPP1ADORA2A | |
| Ammonia Solution, Strong SCHEMBL9124811 | 0.83 | SLC22A6 (0.61) | FGFR1SLC22A6CYP3A4ENPP1FBP1 | |
| SCHEMBL2107417 | 0.83 | FGFR1 (0.68) | FGFR1SLC22A6CYP3A4ENPP1FBP1 | |
| Ammonia Solution, Strong SCHEMBL9124830 | 0.83 | SLC22A6 (0.61) | FGFR1SLC22A6CYP3A4ENPP1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | claimed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | claimed |
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |