Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | FAP | Q12884 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858011 | 0.88 | SLC22A6 (0.43) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9683794 | 0.87 | CYP3A4 (0.41) | SLC22A6CYP3A4FGFR1ENPP1CYP2D6 | |
| SCHEMBL9857534 | 0.86 | FGFR1 (0.57) | SLC22A6CYP3A4FGFR1ENPP1ADORA2A | |
| SCHEMBL9127128 | 0.85 | FAP (0.48) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9417160 | 0.84 | SLC22A6 (0.50) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9858312 | 0.84 | FGFR1 (0.49) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9555527 | 0.83 | FAP (0.44) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9417158 | 0.83 | FAP (0.44) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9555568 | 0.83 | FAP (0.44) | SLC22A6FAPABCB11POLA1POLG | |
| SCHEMBL9858339 | 0.82 | FGFR1 (0.50) | SLC22A6FAPABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | claimed |
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |