Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375286 | 0.78 | — | — | |
| SCHEMBL1149810 | 0.74 | — | — | |
| SCHEMBL16387155 | 0.72 | — | — | |
| SCHEMBL1478683 | 0.71 | — | — | |
| SCHEMBL11229278 | 0.70 | — | — | |
| Diethyl Sulfide SCHEMBL27771169 | 0.70 | TSHR (0.39) | KDM4EALDH1A1CTSDALOX15TSHR | |
| SCHEMBL1709970 | 0.70 | — | — | |
| SCHEMBL721708 | 0.69 | — | — | |
| SCHEMBL10350231 | 0.68 | TSHR (0.40) | ALDH1A1TSHR | |
| Zinc Ion SCHEMBL964381 | 0.67 | FFAR3 (0.39) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193822-B1 | 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(thio-, sulfinyl- and sulfonyl-containing acyl)hydrazides | G.D. Searle & Co. (US) | 1991-03-20 | — | — | EP | claimed |