SCHEMBL9857575

SCHEMBL9857575

Cc1ccc(-c2c(C(=O)c3ccc4ccccc4c3-c3ccc(C)cc3)ccc3ccccc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.51
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
KDM4A O75164 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
KDM4C Q9H3R0 1/20 0.48
MAPT P10636 3/20 0.46
CYP1A2 P05177 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GPR84 Q9NQS5 1/20 0.43
GSK3B P49841 1/20 0.42
ADK P55263 1/20 0.42
LDHA P00338 1/20 0.42
CDC25B P30305 2/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5068744 0.89 WDR5 (0.69) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL9856947 0.86 WDR5 (0.63) WDR5NPC1MEN1KMT2AMAPT
SCHEMBL9857398 0.85 WDR5 (0.53) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL9857384 0.83 ABCG2 (0.50) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL14052470 0.81 MEN1 (0.44) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL9856903 0.80 WDR5 (0.47) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL11623727 0.79 CNR2 (0.50) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL9857422 0.79 WDR5 (0.54) WDR5RAB9ANPC1MEN1KMT2A
SCHEMBL27896431 0.78 WDR5 (0.67) WDR5MEN1KMT2AKDM4ACTDSP1
SCHEMBL27349326 0.77 WDR5 (0.51) WDR5MAPTCYP1A2ALDH1A1LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426846-A1 FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
CN-1040332-A Fluorine-containing aromatic sulfonic acid catalyzer and method for making and purposes MITSUI PETROCHEMICAL IND (JP) 1990-03-14 CN disclosed