Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.57 |
| ▸ | BAD | Q92934 | 2/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.56 |
| ▸ | HNF4A | P41235 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | DCLRE1B | Q9H816 | 2/20 | 0.50 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794588 | 0.91 | DHODH (0.54) | BCL2L1BADACMSDHNF4APTPN1 | |
| SCHEMBL2462821 | 0.91 | ACMSD (0.66) | ACMSDHNF4APTPN1DHFRMCL1 | |
| SCHEMBL10334618 | 0.89 | ACMSD (0.62) | ACMSDHNF4APTPN1DHFRMCL1 | |
| SCHEMBL5024503 | 0.87 | LTB4R2 (0.51) | BCL2L1BADACMSDHNF4APTPN1 | |
| SCHEMBL17797021 | 0.85 | HSD17B10 (0.51) | BCL2L1BADACMSDDHFRDCLRE1B | |
| SCHEMBL31676805 | 0.85 | HSD17B10 (0.51) | BCL2L1BADACMSDDHFRDCLRE1B | |
| SCHEMBL460360 | 0.84 | ACMSD (0.58) | ACMSDHNF4APTPN1DHFRMCL1 | |
| SCHEMBL497304 | 0.82 | SLC6A4 (0.64) | BCL2L1BADACMSDHNF4ALTB4R2 | |
| SCHEMBL21938180 | 0.81 | BCL2L1 (0.54) | BCL2L1BADACMSDDHFRDHODH | |
| SCHEMBL6778159 | 0.81 | HSD17B10 (0.58) | BCL2L1BADACMSDDHFRLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |