Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857659 | 1.00 | TSHR (0.39) | TSHRNPSR1USP2HPGDMAPT | |
| SCHEMBL9857661 | 0.85 | KDM4E (0.40) | MAPTRAB9AKDM4ERXFP1KCNK3 | |
| SCHEMBL10681141 | 0.82 | RAB9A (0.38) | TSHRNPSR1ALDH1A1SRPK1RAB9A | |
| SCHEMBL9857207 | 0.82 | MAOB (0.45) | MAPTALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL6008813 | 0.82 | RAB9A (0.38) | TSHRNPSR1ALDH1A1SRPK1RAB9A | |
| SCHEMBL9857203 | 0.82 | MAOB (0.45) | MAPTALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL6008817 | 0.82 | RAB9A (0.38) | TSHRNPSR1ALDH1A1SRPK1RAB9A | |
| SCHEMBL9857805 | 0.81 | KDM4E (0.40) | MAPTRAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL9857261 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2RAB9AKDM4EKMT2A | |
| SCHEMBL10626882 | 0.76 | NPC1 (0.42) | MAPTALDH1A1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068248-A | Analgesics, antipyretics and antiinflammatory agents | MERCK & CO., INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0160408-B1 | BENZOTHIOPHENES, THEIR PRODUCTION AND USE, AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4760086-A | N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0160408-A1 | Benzothiophenes, their production and use, and compositions containing them | MERCK & CO. INC. (US) | 1985-11-06 | — | — | EP | disclosed |