Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2165602 | 0.97 | FDPS (0.37) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL1242731 | 0.86 | MAPT (0.40) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL27610204 | 0.86 | MAPT (0.40) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL27939231 | 0.86 | FDPS (0.35) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL28252697 | 0.86 | FDPS (0.35) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL7914282 | 0.84 | MAPT (0.39) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL5874245 | 0.84 | FDPS (0.41) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL21616468 | 0.83 | FDPS (0.32) | FDPSMMP1MMP2MMP3MMP9 | |
| Phosphoric Acid SCHEMBL27564760 | 0.82 | FDPS (0.39) | FDPSMMP1MMP2MMP3MMP9 | |
| SCHEMBL27779937 | 0.82 | FDPS (0.39) | FDPSMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-B1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1991-05-22 | — | — | EP | disclosed |