Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526866 | 0.87 | GAA (0.52) | APPTDP1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9487932 | 0.84 | APP (0.52) | APPTDP1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL490553 | 0.84 | CYP4F2 (0.55) | APPALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL197805 | 0.84 | APP (0.76) | APPTDP1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9172620 | 0.83 | KMT2A (0.49) | APPTDP1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL9858174 | 0.83 | FFAR4 (0.44) | APPTDP1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30077234 | 0.83 | APP (0.58) | APPTDP1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL7116001 | 0.83 | APP (0.58) | APPTDP1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL2131066 | 0.83 | APP (0.51) | APPTDP1ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL7933753 | 0.82 | APP (0.57) | APPTDP1ALDH1A1L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077424-A | Antioxidants | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0335262-A2 | Phosphite compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |