Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.67 |
| ▸ | ESRRG | P62508 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | ESRRB | O95718 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | PLD2 | O14939 | 1/20 | 0.67 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857720 | 0.95 | ESR1 (0.63) | ESR1ESR2HDAC6ESRRGMAPT | |
| Pyrophosphoric Acid SCHEMBL9858004 | 0.92 | ESR1 (0.74) | ESR1ESR2HDAC6ESRRGMAPT | |
| Pyrophosphoric Acid SCHEMBL9857991 | 0.92 | ESR1 (0.74) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857990 | 0.87 | ESR1 (0.70) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857837 | 0.85 | ESR1 (0.90) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857247 | 0.85 | ESR1 (0.90) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857240 | 0.85 | ESR1 (0.90) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857632 | 0.84 | ESR1 (0.66) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL14078432 | 0.83 | ESR1 (0.65) | ESR1ESR2HDAC6ESRRGMAPT | |
| SCHEMBL9857878 | 0.83 | ESR1 (0.80) | ESR1ESR2ESRRGMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-B1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1991-05-22 | — | — | EP | claimed |
| US-4897503-A | ANTITUMOR AGENTS; TREATING MAMMARY CANCER AND ANOVULATORY INFERTILITY | TAIHO PHARMACEUTICAL (JP) | 1990-01-30 | — | — | US | claimed |
| EP-0272330-A1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-29 | — | — | EP | claimed |