Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857943 | 0.82 | PPARD (0.44) | PPARDTSHRSMN1; SMN2USP2LPAR5 | |
| SCHEMBL3487454 | 0.78 | PPARD (0.57) | PPARDTSHRSMN1; SMN2THRBMAPT | |
| SCHEMBL8399163 | 0.77 | PPARD (0.56) | PPARDTSHRSMN1; SMN2THRBMAPT | |
| SCHEMBL9858274 | 0.75 | — | — | |
| SCHEMBL30166445 | 0.75 | PPARD (0.53) | PPARDTSHRSMN1; SMN2THRBMAPT | |
| SCHEMBL9304075 | 0.75 | TSHR (0.52) | PPARDTSHRSMN1; SMN2 | |
| SCHEMBL6667187 | 0.75 | — | — | |
| SCHEMBL9858146 | 0.74 | PPARD (0.52) | PPARDTSHRSMN1; SMN2THRBMAPT | |
| SCHEMBL6734576 | 0.74 | PPARD (0.50) | PPARDTSHRSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9499680 | 0.72 | TSHR (0.60) | PPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |