Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417135 | 0.92 | GAA (0.62) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9857509 | 0.86 | RECQL (0.48) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL10439345 | 0.85 | RECQL (0.52) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9684315 | 0.85 | GAA (0.51) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9683399 | 0.84 | GAA (0.50) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL10439191 | 0.83 | RECQL (0.49) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL14439985 | 0.82 | GAA (0.54) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL10497028 | 0.78 | GAA (0.57) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL6570943 | 0.78 | GAA (0.74) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL3431305 | 0.77 | RECQL (0.69) | GAARECQLTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |