Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684315 | 0.96 | GAA (0.51) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL14439985 | 0.90 | GAA (0.54) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL10439191 | 0.88 | RECQL (0.49) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL10439345 | 0.85 | RECQL (0.52) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9858209 | 0.84 | GAA (0.51) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9857509 | 0.81 | RECQL (0.48) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL9417135 | 0.81 | GAA (0.62) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL17019828 | 0.80 | — | — | |
| SCHEMBL10439262 | 0.80 | GAA (0.56) | GAARECQLTDP1ALDH1A1 | |
| SCHEMBL4168183 | 0.79 | TDP1 (0.50) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |