SCHEMBL9858331

SCHEMBL9858331

CCOP(=O)(COCC(O)CO[Si](C)(C)C(C)(C)C)OCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 1/20 0.33
PPARD Q03181 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858274 0.88
SCHEMBL10448201 0.82 LPAR5 (0.33) LPAR5
SCHEMBL9858000 0.82 TSHR (0.31) TSHR
SCHEMBL9684317 0.81 PPARD (0.40) PPARDTSHR
SCHEMBL9858037 0.81 TSHR (0.30) TSHR
SCHEMBL5572087 0.80 KDM4E (0.31) TSHR
SCHEMBL1487020 0.80 KDM4E (0.31) TSHR
SCHEMBL5241702 0.78 KDM4E (0.34)
SCHEMBL9858325 0.76 PPARD (0.34) PPARDTSHR
SCHEMBL4420207 0.76 MAPK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055458-A PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY BEECHAM GROUP P.L.C. (GB) 1991-10-08 US disclosed
EP-0353955-A2 Novel compounds BEECHAM GROUP PLC (GB) 1990-02-07 EP disclosed