Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Menadione Sulfurous Acid SCHEMBL18314150 | 0.87 | POLB (0.67) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL459525 | 0.87 | POLB (0.67) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL2403513 | 0.86 | POLB (0.65) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL459907 | 0.86 | POLB (0.65) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL461202 | 0.86 | POLB (0.65) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL459627 | 0.86 | POLB (0.65) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL461613 | 0.84 | POLB (0.68) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL460404 | 0.84 | POLB (0.68) | POLBMEN1KMT2ARECQLNPSR1 | |
| Menadione Sulfurous Acid SCHEMBL9858607 | 0.79 | KDM4E (0.49) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| Menadione Sulfurous Acid SCHEMBL9857868 | 0.77 | KDM4E (0.55) | POLBMEN1KMT2ARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234940-B1 | NOVEL DERIVATIVES BASED UPON PYRIDO-MENADIONE ADDUCTS AND USES THEREOF | Heterochemical Corporation (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4808602-A | VITAMIN B6 AND VITAMIN K ACTIVITY | HETEROCHEMICAL CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0234940-A2 | Novel derivatives based upon pyrido-menadione adducts and uses thereof | Heterochemical Corporation (US) | 1987-09-02 | — | — | EP | disclosed |