Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | PDXK | O00764 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Menadione Sulfurous Acid SCHEMBL9858437 | 0.93 | LMNA (0.52) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Menadione Sulfurous Acid SCHEMBL9857868 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| Menadione Sulfurous Acid SCHEMBL9858611 | 0.79 | POLB (0.53) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL18314150 | 0.77 | POLB (0.67) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL459525 | 0.77 | POLB (0.67) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL2403513 | 0.76 | POLB (0.65) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL461202 | 0.76 | POLB (0.65) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL459627 | 0.76 | POLB (0.65) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL459907 | 0.76 | POLB (0.65) | KDM4EALDH1A1KMT2AMEN1POLB | |
| Menadione Sulfurous Acid SCHEMBL461613 | 0.74 | POLB (0.68) | KDM4EALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234940-B1 | NOVEL DERIVATIVES BASED UPON PYRIDO-MENADIONE ADDUCTS AND USES THEREOF | Heterochemical Corporation (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4808602-A | VITAMIN B6 AND VITAMIN K ACTIVITY | HETEROCHEMICAL CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0234940-A2 | Novel derivatives based upon pyrido-menadione adducts and uses thereof | Heterochemical Corporation (US) | 1987-09-02 | — | — | EP | disclosed |