SCHEMBL9858742

SCHEMBL9858742

CCN(CC)C(N)=S.CNC(N)=S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 3/20 0.40
EHMT1 Q9H9B1 3/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
ABCB11 O95342 2/20 0.40
HTT P42858 2/20 0.40
GSDMD P57764 2/20 0.40
CA4 P22748 2/20 0.40
CYP2E1 P05181 1/20 0.40
PTGS1 P23219 1/20 0.40
ALDH1A1 P00352 5/20 0.39
PHGDH O43175 3/20 0.39
MGLL Q99685 3/20 0.39
ALDH2 P05091 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
PLIN1 O60240 1/20 0.39
GMNN O75496 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663660 0.87
SCHEMBL96554 0.87
SCHEMBL2115642 0.84
Ammonia Solution, Strong SCHEMBL28157014 0.84 CA12 (0.48) EHMT2EHMT1CA12CA1CA2
SCHEMBL8523302 0.78 ALDH1A1 (0.47) CA12CA1CA2CA9ALDH1A1
SCHEMBL83633 0.74
SCHEMBL9555580 0.72
SCHEMBL8901573 0.71 CA12 (0.57) EHMT2EHMT1CA12CA1CA2
SCHEMBL7718565 0.71
Thiourea SCHEMBL10336650 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981877-A STORAGE STABILITY, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1991-01-01 US disclosed