SCHEMBL9859453

SCHEMBL9859453

CC(O)C(Cn1ccnc1)OC1CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 1/20 0.37
CYP24A1 Q07973 1/20 0.35
FDPS P14324 1/20 0.33
AGER Q15109 1/20 0.33
QPCT Q16769 2/20 0.33
GAA P10253 1/20 0.33
CYP19A1 P11511 1/20 0.33
PDE8B O95263 1/20 0.32
TBXA2R P21731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9859446 0.88 CYP2B6 (0.37) CYP2B6FDPSAGERQPCTGAA
SCHEMBL201199 0.73 CYP2B6 (0.36) CYP2B6FDPSPDE8BTBXA2R
SCHEMBL201200 0.73 CYP2B6 (0.36) CYP2B6FDPSPDE8BTBXA2R
SCHEMBL8295973 0.70 CYP2B6 (0.43) CYP2B6QPCTGAACYP19A1
SCHEMBL10572039 0.68 CYP2B6 (0.39) CYP2B6FDPSQPCTGAAPDE8B
SCHEMBL10922540 0.68 CYP2B6 (0.53) CYP2B6FDPSQPCTGAACYP19A1
SCHEMBL11750410 0.66 CYP2B6 (0.44) CYP2B6FDPSAGERQPCTGAA
SCHEMBL30001033 0.66 MEN1 (0.31)
SCHEMBL2640725 0.66 MEN1 (0.31)
SCHEMBL8079974 0.66 HTT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421210-A2 Triazole compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-04-10 EP disclosed