Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859514 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9859507 | 0.82 | MEN1 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9859506 | 0.82 | KMT2A (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9859498 | 0.82 | KMT2A (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9727128 | 0.78 | HMGCR (0.53) | ALDH1A1 | |
| SCHEMBL9727124 | 0.78 | HMGCR (0.53) | ALDH1A1 | |
| SCHEMBL9726717 | 0.78 | HMGCR (0.53) | ALDH1A1 | |
| SCHEMBL9860022 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9860030 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9855210 | 0.74 | CYP1A2 (0.40) | CYP1A2MAPTCYP2C19SMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |