Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 9/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 6/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195728 | 0.76 | ITGA4 (1.00) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL9810959 | 0.76 | ITGA4 (1.00) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL9671809 | 0.74 | ITGA4 (0.68) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL22380689 | 0.74 | ITGA4 (0.68) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL9672242 | 0.71 | ITGA4 (0.68) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL9671834 | 0.68 | ITGA4 (0.73) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL9673307 | 0.68 | ITGA4 (0.68) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL25063575 | 0.66 | ITGA4 (0.58) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL21095582 | 0.66 | ITGA4 (0.58) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 | |
| SCHEMBL3667326 | 0.66 | AKR1B1 (0.71) | ITGA4AKR1B1AKR1A1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |