Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925342 | 0.81 | PDK2 (0.52) | TDP1THRBPDK2KMT2ACYP1A2 | |
| SCHEMBL6921293 | 0.81 | PDK2 (0.50) | TDP1THRBPDK2KMT2ACYP1A2 | |
| SCHEMBL30488775 | 0.80 | THRB (1.00) | TDP1THRBPDK2KMT2ALMNA | |
| SCHEMBL66735 | 0.80 | THRB (1.00) | TDP1THRBPDK2KMT2ALMNA | |
| SCHEMBL11469925 | 0.80 | THRB (1.00) | TDP1THRBPDK2KMT2ALMNA | |
| Bromide SCHEMBL27743796 | 0.78 | THRB (0.95) | TDP1THRBPDK2KMT2ALMNA | |
| SCHEMBL14099219 | 0.77 | PDK2 (0.55) | TDP1THRBPDK2KMT2ACYP1A2 | |
| Methyl Alcohol SCHEMBL21134117 | 0.76 | THRB (0.91) | TDP1THRBPDK2KMT2AGAA | |
| Bromomethane SCHEMBL208217 | 0.74 | THRB (0.88) | TDP1THRBPDK2KMT2AGAA | |
| SCHEMBL24372357 | 0.74 | KMT2A (0.51) | TDP1THRBPDK2KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |