Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309503 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9859977 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9309742 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9309498 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9309634 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9481078 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL27451816 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL27347129 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9309734 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9308817 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2ABCC4ABCB11PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |